N-叔丁氧羰基-1,2-乙二胺合成路线 （共 68 条）
反应条件
1: in water
T=35°C;
2: With 5 Pd(II)/C(eggshell); hydrogen in water
24 h;
参考文献
Etienne, Marcus A.; Kostochka, Mikhail; Fuselier, Joseph A.; Coy, David H.
Amino Acids, 2012 , vol. 42, # 5 p. 1727 - 1733
反应条件
sodium hydroxide in ethanol
T=20°C;
参考文献
Chen, Yu-Chen; Muhlrad, Andras; Shteyer, Arie; Vidson, Marina; Bab, Itai; Chorev, Michael
Journal of Medicinal Chemistry, 2002 , vol. 45, # 8 p. 1624 - 1632
反应条件
1: in dichloromethane
1 h;
2: With sodium tris(acetoxy)borohydride in dichloromethane
T=20°C; 4 h;
3: With sodium hydroxide; water in ethyl acetate
参考文献
KALYPSYS, INC.
Patent: WO2007/47432 A1, 2007 ;
Location in patent: Page/Page column 29 ;
WO 2007/047432 A2
反应条件
triethanolamine in tetrahydrofuran; ethyl acetate; acetonitrile
参考文献
Proteinix, Inc.
Patent: US2002/146843 A1, 2002 ;
反应条件
triethylamine in dichloromethane
T=0 - 20°C; Inert atmosphere;
参考文献
Kim, Young-Hee; Rhim, Sol; Park, Jin Joo; Kang, Jongmin
Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2012 , vol. 74, # 1-4 p. 317 - 323
反应条件
1: in dichloromethane
18 h;
2: in dichloromethane
4 h;
3: With trifluoroacetic acid
T=20°C; 2 h;
参考文献
Conn, P. Jeffrey; Lindsley, Craig W.; Wood, Michael R.; Gogliotti, Rocco D.; Niswender, Colleen M.; Melancon, Bruce J.; Lebois, Evan P.
Patent: US2011/172227 A1, 2011 ;
Location in patent: Page/Page column 48 ;
反应条件
hydrogenchloride; sodium borohydride; magnesium sulfate; triethylamine in methanol
参考文献
Pfizer Inc
Patent: US2004/92529 A1, 2004 ;
US 20040092529 A1
参考文献
Merck and Co., Inc.
Patent: US6156895 A1, 2000 ;
US 6156895 A
Title/Abstract Full Text Show Details
Merck and Co., Inc.
Patent: US5977364 A1, 1999 ;
US 5977364 A
