2-(1-甲基-1H-苯并咪唑-2-基氨基)-乙醇合成路线 (共 2 条)
反应条件
1: 96 percent / SOCl2 / 1 h / Heating; other reagent (POCl3), other time (2-3 h) 2: 68 percent / NaOH / methanol / 20 °C View Scheme
参考文献
Anisimova, V. A.; Levchenko, M. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1987 , vol. 23, # 1 p. 48 - 52
Khimiya Geterotsiklicheskikh Soedinenii, 1987 , vol. 23, # 1 p. 59 - 63
反应条件
1: 65 percent / 0.25 h / 160 °C
2: 20 percent / LiAlH4 / diethyl ether / 5 h / Heating
View Scheme
参考文献
Da Settimo; Primofiore; Marini
Farmaco, 1992 , vol. 47, # 10 p. 1293 - 1313