3-氯-4-甲氧基-1,2,5-噻二唑合成路线 （共 3 条）
反应条件
potassium carbonate in dimethyl sulfoxide
参考文献
Chemie Linz Aktiengesellschaft
Patent: US4151164 A1, 1979 ;
反应条件
1: methanol With sodium hydride
1 h; Heating;
2: 3,4-Dichloro-1,2,5-thiadiazole in tetrahydrofuran; methanol
T=20°C; 24 h;
参考文献
Cao, Yang; Zhang, Minjia; Wu, Cindy; Lee, Selina; Wroblewski, Mary Elizabeth; Whipple, Trisha; Nagy, Peter I.; Takacs-Novak, Krisztina; Balazs, Attila; Toroes, Szilard; Messer Jr., William S.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4273 - 4286
反应条件
in methanol
Heating;
参考文献
Sabb, Annmarie L; Vogel, Robert L; Kelly, Michael G; Palmer, Yvette; Smith, Deborah L; Andree, Terrance H; Schechter, Lee E
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 8 p. 1069 - 1071
