2-氰基-[1,1-联苯]-4-羧酸合成路线 （共 6 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride; potassium carbonate in 1,4-dioxane
Suzuki coupling; 1 h; Heating;
参考文献
Zhang, Penglie; Bao, Liang; Zuckett, Jingmei F.; Goldman, Erick A.; Jia, Zhaozhong J.; Arfsten, Ann; Edwards, Susan; Sinha, Uma; Hutchaleelaha, Athiwat; Park, Gary; Lambing, Joseph L.; Hollenbach, Stanley J.; Scarborough, Robert M.; Zhu, Bing-Yan
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 4 p. 983 - 987
反应条件
1: AlCl3 / nitrobenzene
2: aq. NaOBr / dioxane
3: Py / dimethylformamide
View Scheme
参考文献
Byron,D.J. et al.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 840 - 845
反应条件
1: aq. NaOBr / dioxane
2: Py / dimethylformamide
View Scheme
参考文献
Byron,D.J. et al.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 840 - 845
反应条件
pyridine in N,N-dimethyl-formamide
参考文献
Byron,D.J. et al.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 840 - 845
反应条件
water in methanol
T=30 - 50°C; ΔH(excit), ΔS(excit), log A; Rate constantThermodynamic dataKinetics;
参考文献
Ananthakrishnanadar, Ponnambalanad.; Kannan, Nagarathnam
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1984 , # 1 p. 35 - 38
反应条件
sulfuric acid
6 h; Heating;
参考文献
Ananthakrishnanadar, Ponnambalanad.; Kannan, Nagarathnam
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1984 , # 1 p. 35 - 38
