(S)-2-环戊基氧基羰基氨基-3,3-二甲基丁酸合成路线 （共 4 条）
反应条件
1: With sodium hydrogencarbonate in water; acetone T=20°C; 4 h; 2: With hydrogenchloride in water pH=2;
参考文献
WO2007/25307 A2, ;
Page/Page column 291-292 ;
WO 2007/025307 A2
反应条件
1: (2S)-2-amino-3,3-dimethylbutanoic acid With trimethylsilyl cyanide in acetonitrile 0.25 h; 2: cyclopentyl Chloroformate in acetonitrile T=80°C;
参考文献
WO2003/99274 A1, ;
Page 505-506 ;
WO 03/099274 A1
反应条件
in tert-Butylamino-acetic acid; sodium hydrogencarbonate; acetone
反应条件
1: pyridine / N,N-dimethyl-formamide / 15 h / 40 °C 2: potassium phosphate / water; N,N-dimethyl-formamide / 20 - 30 °C View Scheme
参考文献
Synlett, , # 10 art. no. S03311ST, p. 1454 - 1458
