3-甲基丁脒盐酸盐(1:1)合成路线 (共 3 条)
参考文献
Ostrogovich; Gheorghiu
Gazzetta Chimica Italiana, 1932 , vol. 62, p. 324
反应条件
1: HCl(g) / 18 h / 25 °C
2: NH3 / ethanol / 72 h / 25 °C
View Scheme
参考文献
Moore, William M.; Webber, R. Keith; Fok, Kam F.; Jerome, Gina M.; Kornmeier, Christine M.; Tjoeng, Foe S.; Currie, Mark G.
Bioorganic and Medicinal Chemistry, 1996 , vol. 4, # 9 p. 1559 - 1564
反应条件
1: With ethanol; sodium
T=20°C; 6 h;
2: With acetic acid in water
T=20°C; pH=5;
参考文献
PALAU PHARMA, S. A.
Patent: WO2009/80721 A2, 2009 ;
Location in patent: Page/Page column 75 ;
WO 2009/080721 A2