4-氨基联苯-4-羧酸甲酯合成路线 （共 8 条）
反应条件
palladium 10 on activated carbon; hydrogen in methanol T=20°C; 15 h;
参考文献
Venkatraj, Muthusamy; Messagie, Jonas; Joossens, Jurgen; Lambeir, Anne-Marie; Haemers, Achiel; Van Der Veken, Pieter; Augustyns, Koen
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 4 p. 1557 - 1568
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethylene glycol dimethyl ether; ethanol; water Suzuki Coupling; 20 h; Inert atmosphereReflux;
参考文献
Wang, Wen-Long; Huang, Chao; Gao, Li-Xin; Tang, Chun-Lan; Wang, Jun-Qing; Wu, Min-Chen; Sheng, Li; Chen, Hai-Jun; Nan, Fa-Jun; Li, Jing-Ya; Li, Jia; Feng, Bainian
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 8 p. 1889 - 1894
反应条件
1: (i) SOCl2, (ii) /BRN= 1098229/ 2: Fe, aq. HCl / methanol View Scheme
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 840 - 845
反应条件
1: aq. NaOBr / dioxane 2: (i) SOCl2, (ii) /BRN= 1098229/ 3: Fe, aq. HCl / methanol View Scheme
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 840 - 845
反应条件
1: AlCl3 / nitrobenzene 2: aq. NaOBr / dioxane 3: (i) SOCl2, (ii) /BRN= 1098229/ 4: Fe, aq. HCl / methanol View Scheme
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 840 - 845
反应条件
1.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / ethanol; water; toluene / 48 h / Inert atmosphere; Reflux 1.2: pH 3 2.1: thionyl chloride / 70 °C 3.1: palladium 10 on activated carbon; hydrogen / methanol / 15 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 20, # 4 p. 1557 - 1568
反应条件
1.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / ethanol; water; toluene / 48 h / Inert atmosphere; Reflux 1.2: pH 3 2.1: thionyl chloride / 70 °C 3.1: palladium 10 on activated carbon; hydrogen / methanol / 15 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 20, # 4 p. 1557 - 1568
反应条件
potassium hydroxide in methanol
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 840 - 845
