1-苄基吡咯烷-3-甲醇合成路线 （共 27 条）
反应条件
1: With dimethylsulfide; borane in toluene T=0 - 110°C; 16 h; Heating / reflux; 2: With sodium hydrogencarbonate in water; toluene T=-10 - 20°C; 2 h; Heating / reflux;
参考文献
RANBAXY LABORATORIES LIMITED
Patent: WO2006/18708 A2, 2006 ;
Location in patent: Page/Page column 21-22 ;
WO 2006/018708 A2
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=0 - 20°C; 2 h; 2: With water in tetrahydrofuran T=0°C;
参考文献
Cumbre Inc.
Patent: US2006/19985 A1, 2006 ;
Location in patent: Page/Page column 17 ;
反应条件
sodium sulfate in tetrahydrofuran
参考文献
Eli Lilly and Company
Patent: US6635657 B1, 2003 ;
US 6635657 B1
反应条件
hydrogenchloride; sodium hydroxide; ammonium formate; N-ethyl-N,N-diisopropylamine; palladium dihydroxide in tetrahydrofuran; methanol; dichloromethane; water; ethyl acetate
参考文献
US6329380 B1, ;
US 6329380 B1
反应条件
sodium hydroxide in tetrahydrofuran; water
反应条件
carbon dioxide in sulfuric acid; water
参考文献
US5556981 A1, ;
US 5556981 A
反应条件
sodium bis(2-methoxyethoxy)aluminium dihydride in tetrahydrofuran; toluene 2.5 h; Heating;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 5 p. 1151 - 1175
反应条件
1: 94 percent / Me3SiI / CCl4 2: 1.) NaHCO3; 2.) t-BuOK / 1.) MeOH; 2.) t-BuOH View Scheme
参考文献
Tetrahedron Letters, , vol. 29, # 28 p. 3481 - 3482
