1-(2-硝基-4-三氟甲基-苯基)-2-丙酮合成路线 （共 7 条）
反应条件
potassium phosphate; N-[2'-(dicyclohexylphosphino)-1,1'-biphenyl-2-yl]-N,N-dimethylamine; phenol; tris-(dibenzylideneacetone)dipalladium(0) in toluene
T=50°C; 9 h;
参考文献
Dainippon Sumitomo Pharma Co., Ltd.
Patent: WO2006/75638 A1, 2006 ;
Location in patent: Page/Page column 66-67 ;
反应条件
tris(dibenzylideneacetone)dipalladium (0) in acetone; toluene
参考文献
Dainippon Sumitomo Pharma Co., Ltd.
Patent: EP1837329 A1, 2007 ;
反应条件
potassium acetate in water; acetone
T=20°C;
参考文献
Molinaro, Carmela; Mowat, Jeffrey; Gosselin, Francis; O'Shea, Paul D.; Marcoux, Jean-Francois; Angelaud, Remy; Davies, Ian W.
Journal of Organic Chemistry, 2007 , vol. 72, # 5 p. 1856 - 1858
反应条件
(i) SOCl2, (ii) NaN3; Multistep reaction;
参考文献
Allais; Meier; Mathieu; et al.
European Journal of Medicinal Chemistry, 1975 , vol. 10, # 2 p. 187 - 199
反应条件
1: (i) NaNO2, H2SO4, (ii) aq. ZnCl2, (iii) /BRN= 1719937/, CuCl2
2: (i) SOCl2, (ii) NaN3
View Scheme
参考文献
Allais; Meier; Mathieu; et al.
European Journal of Medicinal Chemistry, 1975 , vol. 10, # 2 p. 187 - 199
反应条件
carbon monoxide; trans-[(η5-C5H5)Fe(CO)2]2 in toluene
T=120°C; 5 h;
参考文献
Nissan Chemical Industries, LTD.
Patent: US2007/83053 A1, 2007 ;
Location in patent: Page/Page column 7-8 ;
反应条件
titanium chloride in ethanol
参考文献
Dainippon Sumitomo Pharma Co., Ltd.
Patent: EP1837329 A1, 2007 ;
