2-氨基-4-氯-6-乙基嘧啶合成路线 （共 7 条）
反应条件
trichlorophosphate T=70°C; 2 h;
参考文献
US2009/215777 A1, ;
Page/Page column 43; 48 ;
反应条件
1: potassium tert-butylate / methanol / 23 - 60 °C 2: tetraethylammonium chloride; N,N-dimethyl-aniline; trichlorophosphate / acetonitrile / 0.33 h / 110 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 57, # 6 p. 2429 - 2439
反应条件
1: 35 percent aq. NH3 2: 56 percent / I2; aq. NaOH / CHCl3 / 5 h 3: 76 percent / Pd(OAc)2(dppf)2; aq. K2HPO4 / 1,2-dimethoxy-ethane / 24 h / Heating View Scheme
参考文献
Richardson, Marianne L.; Stevens, Malcolm F.G.
Journal of Chemical Research - Part S, 2002 , # 10 p. 482 - 484
参考文献
Todd et al.
Journal of the Chemical Society, 1936 , p. 1557
Full Text Show Details
Huber; Hoelscher
Chemische Berichte, 1938 , vol. 71, p. 87,99
参考文献
Richardson, Marianne L.; Stevens, Malcolm F.G.
Journal of Chemical Research - Part S, 2002 , # 10 p. 482 - 484
反应条件
1: 35 percent aq. NH3
2: 56 percent / I2; aq. NaOH / CHCl3 / 5 h
View Scheme
参考文献
Richardson, Marianne L.; Stevens, Malcolm F.G.
Journal of Chemical Research - Part S, 2002 , # 10 p. 482 - 484
反应条件
in methanol
Heating;
参考文献
Richardson, Marianne L.; Stevens, Malcolm F.G.
Journal of Chemical Research - Part S, 2002 , # 10 p. 482 - 484
