1-(4-丙氧基-苯基)-乙酮合成路线 （共 16 条）
反应条件
1: With morpholine; toluene-4-sulfonic acid; sulfur T=130°C; 5 h; 2: With potassium hydroxide in ethanol Reflux; 3: With hydrogenchloride in water pH=2;
参考文献
PROBIODRUG AG
Patent: US2011/92501 A1, 2011 ;
Location in patent: Page/Page column 112-113 ;
反应条件
hydrogenchloride; formaldehyd; ethanol
参考文献
Celadnik et al.
Archiv der Pharmazie (Weinheim, Germany), 1957 , vol. 290, p. 194,196
Full Text Show Details
Profft
CHEMTECH, 1958 , vol. 10, p. 302,304
参考文献
Profft
CHEMTECH, 1952 , vol. 4, p. 241,243
Full Text Show Details
Bockstahler; Wright
Journal of the American Pharmaceutical Association (1912-1977), 1957 , vol. 46, p. 542,544
反应条件
aniline*ZnCl2 in ethanol
T=150 - 160°C; 1 h;
参考文献
Milart, Piotr; Cislowski, Jerzy
Synthesis, 1984 , # 4 p. 328 - 329
反应条件
pyridinium tribromide in acetic acid
T=55 - 60°C; 0.5 h;
参考文献
Sabatini, Stefano; Kaatz, Glenn W.; Rossolini, Gian Maria; Brandini, David; Fravolini, Arnaldo
Journal of Medicinal Chemistry, 2008 , vol. 51, # 14 p. 4321 - 4330
反应条件
sulfuric acid; water; nitric acid
T=-10°C;
参考文献
Profft; Jumar
Archiv der Pharmazie (Weinheim, Germany), 1956 , vol. 289, p. 90,97
