3-氨基-5-溴吡啶-2-甲腈合成路线 (共 7 条)
反应条件
hydrogenchloride; tin(ll) chloride in water T=20°C;
参考文献
WO2005/42498 A2, ;
Page/Page column 44 ;
WO 2005/042498 A2
参考文献
Journal of the Chemical Society, , p. 2042,2044
反应条件
1: iron-turnings; acetic acid / 100 °C 2: CuCN / 150 °C View Scheme
参考文献
Journal of the Chemical Society, , p. 2042,2044
反应条件
1: sulfuric acid; sodium nitrite; water 2: bromine; phosphorus (III)-bromide / 100 °C 3: iron-turnings; acetic acid / 100 °C 4: CuCN / 150 °C View Scheme
参考文献
Journal of the Chemical Society, , p. 2042,2044
反应条件
1: bromine; phosphorus (III)-bromide / 100 °C 2: iron-turnings; acetic acid / 100 °C 3: CuCN / 150 °C View Scheme
参考文献
Journal of the Chemical Society, , p. 2042,2044
反应条件
1: With hydrogenchloride; sodium nitrite in water T=0°C; 1 h; 2: With copper in water 3: With sodium hydroxide in water
参考文献
ELI LILLY AND COMPANY
Patent: WO2007/87488 A2, 2007 ;
Location in patent: Page/Page column 24 ;
反应条件
sodium acetate 16 h;
参考文献
NEUROGEN CORPORATION
Patent: WO2005/42498 A2, 2005 ;
Location in patent: Page/Page column 44 ;
WO 2005/042498 A2