3-(4-氯苯基)苯丙酮合成路线 （共 35 条）
反应条件
in dichloromethane
T=20°C; 16 h; Inert atmosphere;
参考文献
Pouliot, Martin; Renaud, Philippe; Studer, Armido; Vogler, Thomas; Schenk, Kurt
Angewandte Chemie, International Edition, 2009 , vol. 48, # 33 p. 6037 - 6040
Angewandte Chemie, 2009 , vol. 121, # 33 p. 6153 - 6156
反应条件
tris(triphenylphosphine)ruthenium(II) chloride; potassium hydroxide in 1,4-dioxane
T=80°C; 40 h;
参考文献
Cho, Chan Sik; Kim, Bok Tae; Yoon, Nam Sik
Applied Organometallic Chemistry, 2011 , vol. 25, # 9 p. 695 - 698
反应条件
trifluoroacetic acid
72 h; Heating;
参考文献
Wu, Yan-Chao; Liu, Li; Liu, Yu-Liang; Wang, Dong; Chen, Yong-Jun
Journal of Organic Chemistry, 2007 , vol. 72, # 24 p. 9383 - 9386
反应条件
1: 5.31 g / triethylamine / tetrahydrofuran / 20 °C
2: 76 percent / Cu(I) thiophene-2-carboxylate; Pd(PPh3)4; Cs2CO3 / tetrahydrofuran / 16 h / 45 °C
View Scheme
参考文献
Yu, Ying; Liebeskind, Lanny S.
Journal of Organic Chemistry, 2004 , vol. 69, # 10 p. 3554 - 3557
反应条件
1: tetrahydrofuran / 3 h / 0 - 20 °C
2: 76 percent / Cu(I) thiophene-2-carboxylate; Pd(PPh3)4; Cs2CO3 / tetrahydrofuran / 16 h / 45 °C
View Scheme
参考文献
Yu, Ying; Liebeskind, Lanny S.
Journal of Organic Chemistry, 2004 , vol. 69, # 10 p. 3554 - 3557
反应条件
sodium formate in water
T=100°C; 12 h; chemoselective reaction;
参考文献
Bagal, Dattatraya B.; Qureshi, Ziyauddin S.; Dhake, Kishor P.; Khan, Shoeb R.; Bhanage, Bhalchandra M.
Green Chemistry, 2011 , vol. 13, # 6 p. 1490 - 1494
反应条件
potassium phosphate; Wilkinson's catalyst; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in 1,4-dioxane
T=60°C; 20 h; Inert atmosphere; Overall yield = 94 percent; Overall yield = 114 mg;
参考文献
Jiang, Quanbin; Guo, Tenglong; Wang, Qingfu; Wu, Ping; Yu, Zhengkun
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 9 p. 1874 - 1880
反应条件
sodium hydrogen telluride in ethanol; N,N-dimethyl-formamide
4 h; Ambient temperature;
参考文献
Huang, Xian; Zhang, Han-zhong
Synthetic Communications, 1989 , vol. 19, # 1, 2 p. 97 - 106
反应条件
1.1: sodium hydroxide / 20 °C / Inert atmosphere
2.1: anhydrous magnesium perchlorate; BzImh / toluene / 24 h / 80 °C / Inert atmosphere
2.2: 0.17 h / Irradiation
View Scheme
参考文献
Feng, Yi-Si; Yang, Chun-Yan; Huang, Qiang; Xu, Hua-Jian
Tetrahedron, 2012 , vol. 68, # 25 p. 5053 - 5059
反应条件
1.1: sodium hydroxide / 20 °C / Inert atmosphere
2.1: anhydrous magnesium perchlorate; BzImh / toluene / 24 h / 80 °C / Inert atmosphere
2.2: 0.17 h / Irradiation
View Scheme
参考文献
Feng, Yi-Si; Yang, Chun-Yan; Huang, Qiang; Xu, Hua-Jian
Tetrahedron, 2012 , vol. 68, # 25 p. 5053 - 5059
