反式-7,8-二羟基-7,8-二氢-苯并(a)芘合成路线 （共 9 条）
反应条件
phosphoric acid in methanol T=60°C; 5 h; Yield given. Yields of byproduct given;
参考文献
McCourt, David W.; Roller, Peter P.; Gelboin Harry V.
Journal of Organic Chemistry, 1981 , vol. 46, # 21 p. 4157 - 4161
反应条件
phosphoric acid in methanol
T=60°C; 5 h; Yield given. Yields of byproduct given;
参考文献
McCourt, David W.; Roller, Peter P.; Gelboin Harry V.
Journal of Organic Chemistry, 1981 , vol. 46, # 21 p. 4157 - 4161
反应条件
<b>Multi-step reaction with 4 steps<br /> </b>1: 88 percent / MeSO<sub>3</sub>H / CH<sub>2</sub>Cl<sub>2</sub> / 0 °C<br />2: 86 percent / BBr<sub>3</sub> / CH<sub>2</sub>Cl<sub>2</sub> / -20 - 20 °C<br />3: 92.2 percent / o-iodoxybenzoic acid / dimethylformamide / 1 h / 20 °C<br />4: NaBH<sub>4</sub>; O<sub>2</sub> <br /> <br />
参考文献
Harvey, Ronald G.; Dai, Qing; Ran, Chongzhao; Penning, Trevor M. Journal of Organic Chemistry, 2004 , vol. 69, # 6 p. 2024 - 2032
反应条件
<b>With</b> <a href="#" onclick="return RXDsubstances(event, this, '11343078', constants.ctx, '0')">sodium tetrahydroborate</a> <b>in</b> <a href="#" onclick="return RXDsubstances(event, this, '1718733', constants.ctx, '0')">ethanol</a> <br />3 h; Ambient temperature; <br />
参考文献
Platt, Karl L.; Oesch, Franz Journal of Organic Chemistry, 1983 , vol. 48, # 2 p. 265 - 268
反应条件
<b>With</b> <a href="#" onclick="return RXDsubstances(event, this, '3592982', constants.ctx, '0')">sodium methylate</a> <br /> <br />
参考文献
Iyer, Radhakrishnan P.; Slaga, Thomas J.; Pal, Bimal C. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 4 p. 275 - 278
反应条件
<b>Multi-step reaction with 2 steps<br /> </b>1: 92.2 percent / o-iodoxybenzoic acid / dimethylformamide / 1 h / 20 °C<br />2: NaBH<sub>4</sub>; O<sub>2</sub> <br /> <br />
参考文献
Harvey, Ronald G.; Dai, Qing; Ran, Chongzhao; Penning, Trevor M. Journal of Organic Chemistry, 2004 , vol. 69, # 6 p. 2024 - 2032
反应条件
<b>Multi-step reaction with 5 steps<br /> </b>1: 95 percent / t-BuOK / diethyl ether; tetrahydrofuran / 20 °C<br />2: 88 percent / MeSO<sub>3</sub>H / CH<sub>2</sub>Cl<sub>2</sub> / 0 °C<br />3: 86 percent / BBr<sub>3</sub> / CH<sub>2</sub>Cl<sub>2</sub> / -20 - 20 °C<br />4: 92.2 percent / o-iodoxybenzoic acid / dimethylformamide / 1 h / 20 °C<br />5: NaBH<sub>4</sub>; O<sub>2</sub> <br /> <br />
参考文献
Harvey, Ronald G.; Dai, Qing; Ran, Chongzhao; Penning, Trevor M. Journal of Organic Chemistry, 2004 , vol. 69, # 6 p. 2024 - 2032
反应条件
<b>Multi-step reaction with 4 steps<br /> </b>1: 60 percent / I<sub>2</sub>; 1,2-epoxybutane / benzene / 1 h / Irradiation<br />2: 86 percent / BBr<sub>3</sub> / CH<sub>2</sub>Cl<sub>2</sub> / -20 - 20 °C<br />3: 92.2 percent / o-iodoxybenzoic acid / dimethylformamide / 1 h / 20 °C<br />4: NaBH<sub>4</sub>; O<sub>2</sub> <br /> <br />
参考文献
Harvey, Ronald G.; Dai, Qing; Ran, Chongzhao; Penning, Trevor M. Journal of Organic Chemistry, 2004 , vol. 69, # 6 p. 2024 - 2032
反应条件
<b>Multi-step reaction with 4 steps<br /> </b>1: 60 percent / I<sub>2</sub> <br />2: 57 percent / NBS<br />3: 50 percent / xylene<br />4: NaOMe<br /> <br />
参考文献
Iyer, Radhakrishnan P.; Slaga, Thomas J.; Pal, Bimal C. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 4 p. 275 - 278
