1,3-二甲基-1氢-吡唑-5-甲酸合成路线 （共 14 条）
反应条件
1: With sodium hydroxide; water T=0 - 20°C; 18 h; 2: With hydrogenchloride in water T=0 - 20°C; 25 h; Product distribution / selectivity;
参考文献
PFIZER INC.
Patent: WO2006/48761 A2, 2006 ;
Location in patent: Page/Page column 33 ;
WO 2006/048761 A2
反应条件
sodium hydroxide in ethanol; water 1 h; Heating;
参考文献
Australian Journal of Chemistry, , vol. 36, # 1 p. 135 - 147
反应条件
1: N2H4 / H2O 3: NaOH / H2O View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 6, # 15 p. 1819 - 1824
反应条件
2: NaOH / H2O View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 6, # 15 p. 1819 - 1824
反应条件
diethyl ether; phenyllithium anschliessend mit festem CO2 bei -70grad;
参考文献
Justus Liebigs Annalen der Chemie, , vol. 625, p. 55,60
参考文献
Chemische Berichte, , vol. 59, p. 609
参考文献
Chemische Berichte, , vol. 59, p. 609
反应条件
thionyl chloride Heating;
参考文献
Allergan, Inc.
Patent: US2007/32478 A1, 2007 ;
Location in patent: Page/Page column 79 ;
US 20070032478 A1
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
