3-甲基丁炔醇-3-D6合成路线

参考文献

CONCERT PHARMACEUTICALS, INC.; HARBESON, Scott, L.; TUNG, Roger, D.; LIU, Julie, F.
Patent: WO2011/11712 A1, 2011 ;
Location in patent: Page/Page column 41-42 ;
WO 2011/011712 A1

593-60-2溴乙烯+

666-52-4氘代丙酮

57444-27-63-甲基丁炔醇-3-D6

参考文献

Wadsworth, Alan H.; Lawrie, Kenneth W. M.
Journal of Labelled Compounds and Radiopharmaceuticals, 2007 , vol. 50, # 5-6 p. 473 - 474

865-50-9氘代碘甲烷+

623-47-2丙炔酸乙酯

57444-27-63-甲基丁炔醇-3-D6

参考文献

Pasto, Daniel J.; Warren, Steven E.
Journal of Organic Chemistry, 1981 , vol. 46, # 14 p. 2842 - 2846

666-52-4氘代丙酮+

74-86-2乙炔

57444-27-63-甲基丁炔醇-3-D6

参考文献

Kolbe, Adelheid; Fuchs, Petra; Porzel, Andrea; Baumeister, Ute; Kolbe, Alfred; Adam, Guenter
Journal of the Chemical Society. Perkin Transactions 1, 2002 , # 17 p. 2022 - 2027

666-52-4氘代丙酮+

4301-14-8乙炔基溴化镁

57444-27-63-甲基丁炔醇-3-D6

参考文献

Wadsworth, Alan H.; Lawrie, Kenneth W. M.
Journal of Labelled Compounds and Radiopharmaceuticals, 2007 , vol. 50, # 5-6 p. 473 - 474

666-52-4氘代丙酮+

2386-64-3乙基氯化镁

57444-27-63-甲基丁炔醇-3-D6

参考文献

Stanjek, Volker; Miksch, Martin; Boland, Wilhelm
Tetrahedron, 1997 , vol. 53, # 52 p. 17699 - 17710