3-(吡咯烷-2-基)吡啶合成路线 （共 38 条）
反应条件
hydrogen; palladium 10 on activated carbon in methanol 5 h;
参考文献
Divi's Laboratories Limited
Patent: EP2487172 A1, 2012 ;
Location in patent: Page/Page column 4 ;
反应条件
hydrogen; palladium 10 on activated carbon in methanol P=760.051 Torr; 5 h;
参考文献
Divi's Laboratories Limited
Patent: US2012/209006 A1, 2012 ;
Location in patent: Page/Page column 3 ;
反应条件
naphthalene; sodium in tetrahydrofuran T=-78°C;
参考文献
Trost, Barry M.; Marrs, Christopher M.
Journal of the American Chemical Society, 1993 , vol. 115, # 15 p. 6636 - 6645
反应条件
hydrogen; palladium on activated charcoal in acetic acid
参考文献
Murahashi, Shun-Ichi; Mitsui, Hitoshi; Shiota, Tatsuki; Tsuda, Tomoyasu; Watanabe, Shoji
Journal of Organic Chemistry, 1990 , vol. 55, # 6 p. 1736 - 1744
反应条件
hydrogen; triethylamine; palladium on activated charcoal in ethanol P=760.051 Torr;
参考文献
Journal of Organic Chemistry, , vol. 66, # 12 p. 4115 - 4121
反应条件
1.1: NaH / tetrahydrofuran 1.2: HCl 1.3: NaOH 2.1: NaBH4; AcOH / methanol View Scheme
参考文献
Journal of the American Chemical Society, , vol. 124, # 13 p. 3220 - 3221
反应条件
1: 1.) O3, 2.) NaBH4 / 1.) CH2Cl2, CH3OH, -78 deg C, 10 min, 2.) CH2Cl2, CH3OH, -78 deg C, 10 min 2: 77 percent / pyridine, DMAP / CH2Cl2 / 40 °C 3: 81 percent / BuSnH, AlBN / toluene / 90 °C 4: 52 percent / Na, naphthalene / tetrahydrofuran / -78 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 115, # 15 p. 6636 - 6645
反应条件
1: 77 percent / pyridine, DMAP / CH2Cl2 / 40 °C 2: 81 percent / BuSnH, AlBN / toluene / 90 °C 3: 52 percent / Na, naphthalene / tetrahydrofuran / -78 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 115, # 15 p. 6636 - 6645
反应条件
1: 81 percent / BuSnH, AlBN / toluene / 90 °C 2: 52 percent / Na, naphthalene / tetrahydrofuran / -78 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 115, # 15 p. 6636 - 6645
反应条件
1.1: 94 percent / aq. H2SO4 / 18 h / Heating 2.1: sodium hydride / tetrahydrofuran / 1 h / Heating 2.2: 72 percent / aq. HCl / Heating 3.1: 81 percent / NaBH4 / methanol; acetic acid / -40 - 20 °C 4.1: Et3N; H2 / Pd/C / ethanol / 760.05 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 12 p. 4115 - 4121
