4-(4-氟-2-甲基-1H-吲哚-5-基氧基)-6-甲氧基喹唑啉-7-醇合成路线 (共 2 条)
反应条件
hydrogen; palladium on activated charcoal in methanol T=20°C; 24 h;
参考文献
Qian, Changgeng; Cai, Xiong; Zhai, Haixiao
Patent: US2009/76044 A1, 2009 ;
Location in patent: Page/Page column 28 ;
US 20090076044 A1
反应条件
hydrogen; palladium 10 on activated carbon in 1-methyl-pyrrolidin-2-one; water T=50°C; P=3000.3 Torr; 2.75 h; Product distribution / selectivity;
参考文献
WO2008/53221 A2, ;
Page/Page column 55-56 ;
WO 2008/053221 A2