3-甲酰基吲哚酸-1-羧酸 t-丁基酯合成路线 （共 20 条）
反应条件
sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate in dichloromethane T=0°C; Substitution; 1.83333 h;
参考文献
Lee, Jong Seok; Shin, Junho; Lee, Hyi-Seung; Shin, Hee Jae; Lee, Yeon-Ju
Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 2 p. 357 - 358
反应条件
4 A molecular sieve; polymer intercalated (RuCl2(PPh3)3) in acetone T=30°C; 2 h;
参考文献
Kobayashi, Shu; Miyamura, Hiroyuki; Akiyama, Ryo; Ishida, Tasuku
Journal of the American Chemical Society, 2005 , vol. 127, # 25 p. 9251 - 9254
反应条件
tetrabutylammomium bromide in tetrahydrofuran
参考文献
Indiana University Foundation
Patent: US5554753 A1, 1996 ;
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane T=20°C; 1 h;
参考文献
BARTOLOZZI, Alessandra; CHEN, Zhidong; DINES, Jonathon Alan; LO, Ho Yin; LOKE, Pui Leng; OLAGUE, Alan; RIETHER, Doris; TYE, Heather; WU, Lifen; ZINDELL, Renee M.
Patent: US2013/196967 A1, 2013 ;
Location in patent: Paragraph 0224; 0225 ;
反应条件
bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; triethylamine in tetrahydrofuran T=110°C; 24 h; Sealed tube; chemoselective reaction;
参考文献
Journal of Organic Chemistry, , vol. 77, # 22 p. 10272 - 10284
反应条件
tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; triethylamine; tris-(o-tolyl)phosphine in toluene T=110°C; Sealed tube; chemoselective reaction;
参考文献
Journal of Organic Chemistry, , vol. 77, # 22 p. 10272 - 10284
反应条件
1.1: trichlorophosphate / 0.67 h / 0 °C 1.2: 1.33 h / 10 - 35 °C 2.1: 4-(N,N-dimethlyamino)pyridine / acetonitrile / 2 h / 20 °C View Scheme
参考文献
Journal of Enzyme Inhibition and Medicinal Chemistry, , vol. 26, # 2 p. 261 - 269
反应条件
potassium hydroxide in tetrahydrofuran; water 6 h; Ambient temperature;
参考文献
Liebigs Annalen der Chemie, , # 2 p. 413 - 417
反应条件
potassium phosphate in methanol T=120°C; P=5171.62 Torr; 0.0333333 h; Microwave irradiation;
参考文献
Dandepally, Srinivasa Reddy; Williams, Alfred L.
Tetrahedron Letters, 2009 , vol. 50, # 9 p. 1071 - 1074
反应条件
1: 98 percent / NH2OH*HCl, Na2CO3 / ethanol; H2O / 0.08 h / 50 °C 2: 75 percent / NiCl2*6H2O, NaBH4 / methanol / 0.08 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 54, # 14 p. 3549 - 3566
