4-乙酰基-4'-甲基联苯合成路线 （共 60 条）
反应条件
copper(l) iodide; lithium chloride; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; N,N-dimethyl-formamide T=80°C; Stille coupling; 3 h;
参考文献
Hoshino, Masahide; Degenkolb, Peter; Curran, Dennis P.
Journal of Organic Chemistry, 1997 , vol. 62, # 24 p. 8341 - 8349
反应条件
potassium fluoride; bis(benzonitrile)palladium(II) dichloride in tetrahydrofuran T=25°C; Suzuki-Miyaura Coupling; 16 h; Inert atmosphereSealed tube;
参考文献
Iwai, Tomohiro; Tanaka, Ryotaro; Harada, Tomoya; Sawamura, Masaya
Chemistry - A European Journal, 2014 , vol. 20, # 4 p. 1057 - 1065
反应条件
potassium acetate; palladium diacetate; N,N-dicyclohexylamine in N,N-dimethyl-formamide T=35°C; 2 h; Inert atmosphere;
参考文献
Rao, Maddali L.N.; Banerjee, Debasis; Dhanorkar, Ritesh J.
Tetrahedron Letters, 2010 , vol. 51, # 47 p. 6101 - 6104
反应条件
1: 4-bromorophenylboronic acid MIDA ester; p-methylphenylboronic acid With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) in 1,4-dioxane T=100°C; 12 h; 2: para-bromoacetophenone in 1,4-dioxane T=100°C; 12 h;
参考文献
US2009/30238 A1, ;
Page/Page column 23-24 ;
反应条件
[Pd(N3)(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)(N,N'-dimethylbenzylamine(-H))]; tetrabutylammomium bromide; caesium carbonate in ethanol T=120°C; Suzuki-Miyaura Coupling; 0.5 h; Inert atmosphereHeating; Catalytic behavior;
参考文献
Kim, Yong-Joo; Lee, Jung-Hyun; Kim, Taejung; Ham, Jungyeob; Zheng, Zhen Nu; Lee, Soon W.
European Journal of Inorganic Chemistry, 2012 , # 36 p. 6011 - 6017
反应条件
potassium phosphate; triphenylphosphine; palladium diacetate in N,N-dimethyl-formamide T=90°C; 1 h;
参考文献
Rao, Maddali L.N.; Banerjee, Debasis; Jadhav, Deepak N.
Tetrahedron Letters, 2007 , vol. 48, # 15 p. 2707 - 2711
反应条件
NiCl2[(4-MeOPh)3P]2; K3PO4*3H2O; tris(4-methoxyphenyl)-phosphine in toluene T=110°C; 6 h; Inert atmosphere;
参考文献
Chen, Xiaofeng; Ke, Haihua; Zou, Gang
ACS Catalysis, 2014 , vol. 4, # 2 p. 379 - 385
反应条件
silver(l) oxide; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=60°C; Arylation; cross-coupling; 7 h;
参考文献
Hirabayashi, Kazunori; Kondo, Tatsuhiro; Toriyama, Fumihiko; Nishihara, Yasushi; Mori, Atsunori
Bulletin of the Chemical Society of Japan, 2000 , vol. 73, # 3 p. 749 - 750
反应条件
caesium carbonate; triphenylphosphine; palladium dichloride in N,N-dimethyl acetamide T=90°C; 2 h;
参考文献
Rao, Maddali L.N.; Jadhav, Deepak N.; Banerjee, Debasis
Tetrahedron, 2008 , vol. 64, # 24 p. 5762 - 5772
反应条件
caesium carbonate; triphenylphosphine; palladium dichloride in N,N-dimethyl acetamide T=90°C; 1 h;
参考文献
Rao, Maddali L.N.; Jadhav, Deepak N.; Banerjee, Debasis
Tetrahedron, 2008 , vol. 64, # 24 p. 5762 - 5772
