4-乙酰基-4'-甲基联苯合成路线 （共 60 条）
反应条件
1: With potassium phosphate; Ni(PCy3)2Br2 in tetrahydrofuran T=20°C; Suzuki coupling; Inert atmosphere; 2: With water in tetrahydrofuran T=20°C; Suzuki coupling;
参考文献
Advanced Synthesis and Catalysis, , vol. 353, # 11-12 p. 2051 - 2059
反应条件
1.1: sodium hexafluorosilicate / 1 h / 200 °C / Inert atmosphere 2.1: tetrabutyl ammonium fluoride; palladium diacetate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl / tert-butyl alcohol / 0.08 h / 20 °C / Inert atmosphere; Sealed vial 2.2: 60 °C / Inert atmosphere; Sealed vial View Scheme
参考文献
Journal of Organic Chemistry, , vol. 76, # 21 p. 9182 - 9187
反应条件
1: hydrogenchloride / water 2: triphenyl phosphite; K3PO4*3H2O; palladium diacetate; Ipr.HCl / tert-butyl alcohol / 6 h / 80 °C / |Inert atmosphere View Scheme
参考文献
Journal of Organic Chemistry, , vol. 77, # 17 p. 7572 - 7578
反应条件
1: sodium sulfate / tetrahydrofuran / 24 h / 20 °C / |Schlenk technique; |Inert atmosphere 2: bis-triphenylphosphine-palladium(II) chloride; potassium hydroxide / neat (no solvent) / 24 h / 20 °C / |Schlenk technique; |Inert atmosphere View Scheme
参考文献
Advanced Synthesis and Catalysis, , vol. 355, # 18 p. 3553 - 3557
反应条件
aluminium trichloride in chloroform; chlorobenzene
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 34, # 3 p. 977 - 980,969 - 971
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; potassium phosphate; n-butyllithium; 1,1'-bis(diphenylphosphanyl)ferrocenenickel(II) chloride; potassium iodide 1.) toluene, room temperature, 30 min, 2.) toluene, 80 deg C, 16 h; Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 54, # 43 p. 13079 - 13086
反应条件
potassium carbonate T=80°C; Suzuki Coupling; P=760.051 Torr; 7 h; Catalytic behavior;
参考文献
New Journal of Chemistry, , vol. 38, # 4 p. 1471 - 1476
反应条件
Friedel-Crafts acetylation;
参考文献
Chemistry Letters, , p. 519 - 522
反应条件
in 1,4-dioxane; water T=30°C; Equilibrium constant;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 749 - 750
参考文献
Saigo, Kazuhiko; Lin, Ru-Jang; Kubo, Masataka; Youda, Akira; Hasegawa, Masaki
Chemistry Letters, 1986 , p. 519 - 522
