lithium aluminium tetrahydride in tetrahydrofuran T=0 - 60°C; 1 h;

1: ammonium acetate; Ac2O; AcOH / AcONa / 2 h / Heating 2: LiAlH4 / tetrahydrofuran; diethyl ether / 5.5 h / Heating View Scheme

lithium aluminium tetrahydride in tetrahydrofuran T=20°C;

tetrahydrofuran; acetic acid Hydrieren des erhaltenen <6-Fluor-indol-3-yl>-acetonitrils an Raney Nickel in methanol NH3;

1: 2-(6-fluoro-1H-indol-3-yl)ethanamine With hydrogenchloride in tetrahydrofuran; ethyl acetate T=20°C; 2: formyl formic acid With potassium hydroxide in water T=80°C; 1.5 h; 3: With hydrogenchloride; sodium hydroxide more than 3 stages;