5-硝基-2-噻吩甲酸乙酯合成路线 (共 7 条)
反应条件
nitric acid; acetic anhydride; acetic acid
参考文献
Gauthier; Maillard
Annales Pharmaceutiques Francaises, 1953 , vol. 11, p. 509,518
反应条件
1: 5-nitrothiophene-2-carboxylic acid With thionyl chloride
3 h; Heating / reflux;
2: ethanol 3 h; Heating / reflux;
参考文献
Aventis Pharma S.A.
Patent: US2005/154048 A1, 2005 ;
Location in patent: Page/Page column 20 ;
参考文献
American Cyanamid Company
Patent: US4382143 A1, 1983 ;
反应条件
1: concentrated aqueous hydrochloric acid
2: diethyl ether
View Scheme
参考文献
Dann
Chemische Berichte, 1943 , vol. 76, p. 419,428
参考文献
Dann
Chemische Berichte, 1943 , vol. 76, p. 419,428
反应条件
iron in acetic acid
T=90°C; 18 h;
参考文献
ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA
Patent: WO2005/23819 A1, 2005 ;
Location in patent: Page/Page column 50-51 ;
参考文献
Carrara et al.
Gazzetta Chimica Italiana, 1952 , vol. 82, p. 652,655, 660