1: With Amberlyst(R) 15 in dichloromethane T=20°C; 2: With ammonium hydroxide in methanol T=20°C; 1.5 h;

phosphorus pentoxide; triethyl amine hydrochloride; bis-(2-hydroxy-ethyl)-amine T=240°C; 0.5 h;

potassium carbonate in diethylene glycol dimethyl ether 48 h; Heating;

bis (triortho-tolylphosphine)palladium(II) chloride; sodium t-butanolate in diethylene glycol dimethyl ether T=170°C; 48 h; Inert atmosphere;

in various solvent(s) T=150°C;

P2O5

1.1: tri-tert-butylphosphine; palladium(II) acetate; sodium tert-butoxide / xylene / 50 °C 1.2: 100 percent / macroporous polymer-supported isocyanate / xylene / 24 h / 50 °C 2.1: Amberlyst(R) 15 / CH2Cl2 / 20 °C 2.2: 65 percent / aq. NH3 / methanol / 1.5 h / 20 °C View Scheme

sodium hydrogencarbonate