palladium on activated charcoal; ethanol Hydrogenation;

sodium hydroxide 24 h; Heating;

1: K2CO3 / dimethylformamide / 4 h / 100 - 135 °C 2: trifluoroacetic acid / Ambient temperature View Scheme

trifluoroacetic acid Ambient temperature;

sodium acetate; acetic anhydride

sodium hydroxide Heating;

1: With diphenyl phosphoryl azide; triethylamine in dichloromethane; toluene T=60 - 70°C; 1.5 h; 2: With hydrogenchloride; water in dichloromethane; toluene 2 h; Heating / reflux;

1: 92.5 percent / K2CO3 / acetone / 4 h / Heating 2: 50.5 percent / TiCl4 / CH2Cl2 / 1 h / Ambient temperature 3: 83 percent / 10percent aq. K2CO3 / Heating 4: 77 percent / Cu powder / quinoline / Heating 5: 59 percent / BCl3 / CH2Cl2 / 1 h / 0 °C 6: 92 percent / piperidine / ethanol / 20 h / Heating View Scheme

potassium carbonate in acetone 4 h; Heating;