6-甲氧基-2H-色烯-3-甲腈合成路线 （共 6 条）
反应条件
anhydrous sodium hydrogen carbonate in acrylonitrile
反应条件
1,4-diaza-bicyclo[2.2.2]octane 20 h; Heating;
参考文献
Wise, Lawrence D.; DeWald, Horace A.; Hawkins, Elma S.; Reynolds, Donna M.; Heffner, Thomas G.; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 3 p. 688 - 691
反应条件
1: 92 percent / H2 / 10 percent Pd-C / methanol / 22 h / 2585.74 Torr / room t. 2: 76 percent / LiAlH4 / diethyl ether / 5 h / Heating View Scheme
参考文献
Viaud; Mamai; Guerin; Bennejean; Renard; Delagrange; Guardiola-Lemaitre; Howell; Guillaumet
Pharmacy and Pharmacology Communications, 1998 , vol. 4, # 1 p. 47 - 56
反应条件
1: With sodium hydroxide 6 h; Reflux; 2: With hydrogenchloride in water
参考文献
Contino, Marialessandra; Cantore, Mariangela; Capparelli, Elena; Perrone, Maria Grazia; Niso, Mauro; Inglese, Carmela; Berardi, Francesco; Leopoldo, Marcello; Perrone, Roberto; Colabufo, Nicola Antonio
ChemMedChem, 2012 , vol. 7, # 3 p. 391 - 395
反应条件
1: 74 percent / aq. sodium hydroxide / 6 h / Heating 2: 1.) triethylamine, diphenyl phosphorazidate, 2.) conc. HCl / 1.) toluene, 80-85 deg C, 1.5 h, 2.) reflux, 2 h View Scheme
参考文献
Wise, Lawrence D.; DeWald, Horace A.; Hawkins, Elma S.; Reynolds, Donna M.; Heffner, Thomas G.; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 3 p. 688 - 691
反应条件
hydroxylamine hydrochloride; sodium hydrogencarbonate in ethanol; water
3 h; Heating;
参考文献
Riffaud; Dupont; Rene; Royer
European Journal of Medicinal Chemistry, 1982 , vol. 17, # 6 p. 577 - 581
