2H-1-苯并吡喃-3-羧醛, 7-(二乙基氨基)-2-氧代-合成路线 （共 7 条）
反应条件
1: methanol / 4 h / Reflux 2: Cu(II) perchlorate / water; acetonitrile View Scheme
参考文献
Ezeh, Vivian C.; Harrop, Todd C.
Inorganic Chemistry, 2013 , vol. 52, # 5 p. 2323 - 2334
反应条件
1: N,N-dimethyl-formamide With trichlorophosphate
2: 7-diethylamino-coumarin T=60°C; 12 h;
参考文献
Lacivita, Enza; Masotti, Anna Carmela; Jafurulla, Md.; Saxena, Roopali; Rangaraj, Nandini; Chattopadhyay, Amitabha; Colabufo, Nicola A.; Berardi, Francesco; Perrone, Roberto; Leopoldo, Marcello
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 22 p. 6628 - 6632
反应条件
trichlorophosphate in N-methyl-acetamide; (2S)-N-methyl-1-phenylpropan-2-amine hydrate
参考文献
Bayer Aktiengesellschaft
Patent: US4018796 A1, 1977 ;
反应条件
1: 84 percent / piperidine / ethanol / 6 h / Heating
2: 1.) OsO4, 2.) NaIO4 / 1.) THF, H2O, t-BuOH, 1 h, 2.) THF, H2O, t-BuOH, 24 h
View Scheme
参考文献
Padmanabhan; Peri; Triggle
Synthetic Communications, 1996 , vol. 26, # 4 p. 827 - 831
反应条件
water-d2; mercury dichloride in acetonitrile-D3
T=20°C;
参考文献
Kim, Ja Hyung; Kim, Hyun Jung; Kim, Sang Hoon; Lee, Jae Hong; Do, Jung Ho; Kim, Hae-Jo; Lee, Joung Hae; Kim, Jong Seung
Tetrahedron Letters, 2009 , vol. 50, # 43 p. 5958 - 5961
反应条件
1: N,N-dimethyl-formamide With trichlorophosphate
T=40 - 50°C; 0.75 h;
2: 7-diethylaminocoumarin-3-carboxylic acid T=60°C; Vilsmeier Reaction; 2 h;
参考文献
An, Kyoung Lyong; Shin, Seung Rim; Jun, Kun; Park, Soo Youl
Journal of the Korean Chemical Society, 2014 , vol. 58, # 3 p. 297 - 302
反应条件
1: 87 percent / conc. aq. HCl / 10 h / Heating
2: 67 percent / POCl3 / 3 h / 80 °C
View Scheme
参考文献
Komlev, I. V.; Tavrizova, M. A.; Khrolova, O. R.; Mikhailova, T. A.
J. Gen. Chem. USSR (Engl. Transl.), 1985 , vol. 55, # 4 p. 888 - 892,793 - 796
