2-(2-甲氧基苯基)-4,4-二甲基-2-噁唑啉合成路线 (共 54 条)
反应条件
in diethyl ether
18 h; Ambient temperature;
参考文献
Griffiths, D. Vaughan; Griffiths, Penelope A.; Karim, Khalku; Whitehead, Belinda J.
Journal of Chemical Research, Miniprint, 1996 , # 4 p. 901 - 925
反应条件
1: tetrahydrofuran; diethyl ether / 3.5 h / Ambient temperature
2: nitromethane / 70 °C
3: 1.) NaBH4; 2.) 5percent aq. HCl / 1.) EtOH, RT, 4 h; 2.) 65 deg C, 20 min
View Scheme
参考文献
Nate; Sekine; Honma; Nakai; Wada; Takeda; Yabana; Nagao
Chemical and pharmaceutical bulletin, 1987 , vol. 35, # 5 p. 1953 - 1968
反应条件
lithium amide in tetrahydrofuran
参考文献
Meyers,A.I.; Gabel,R.
Journal of Organic Chemistry, 1977 , vol. 42, p. 2653 - 2654
反应条件
1: 62 percent / diethyl ether / 18 h / Ambient temperature
2: 86 percent / conc. aq. HCl / 24 h / Heating
3: SOCl2
View Scheme
参考文献
Griffiths, D. Vaughan; Griffiths, Penelope A.; Karim, Khalku; Whitehead, Belinda J.
Journal of Chemical Research, Miniprint, 1996 , # 4 p. 901 - 925