2-溴-1,3,5-三甲基苯合成路线 （共 240 条）
参考文献
Fuson; Denton
Journal of the American Chemical Society, 1941 , vol. 63, p. 654
反应条件
1: With magnesium in tetrahydrofuran T=-78.16°C; Inert atmosphere; 2: With phosphorus trichoride in tetrahydrofuran T=-78.16 - 20°C; Inert atmosphere;
参考文献
Reissmann, Matti; Schaefer, Andre; Jung, Sebastian; Mueller, Thomas
Organometallics, 2013 , vol. 32, # 22 p. 6736 - 6744
反应条件
copper(l) iodide; tributyl-amine; potassium tert-butylate in tetrahydrofuran T=20°C;
参考文献
Angewandte Chemie, International Edition, , vol. 48, p. 5350 - 5354
Angewandte Chemie, , vol. 121, p. 5454 - 5458
反应条件
copper(l) iodide; tributylphosphine; potassium tert-butylate in tetrahydrofuran byproducts: KBr, Me3C6H3; react. of (B(OCH2)2C(CH3)2)2 (1.5 equiv.), 2,4,6-Me3C6H2Br (1 equiv.), CuI (10 molpercent), nBu3P (13 molpercent) and KOtBu (1.5 equiv.) at room temp.; detd. by XRD;
参考文献
Angewandte Chemie, International Edition, , vol. 48, p. 5350 - 5354
Angewandte Chemie, , vol. 121, p. 5454 - 5458
反应条件
tert.-butyl lithium in tetrahydrofuran; N,N-dimethyl-formamide
参考文献
Sterling Winthrop Inc.
Patent: US5554620 A1, 1996 ;
反应条件
1.1: magnesium / tetrahydrofuran 1.2: phosphorus trichloride / tetrahydrofuran / -78 - 20 °C 2.1: 1.05 g / lithium aluminum hydride / tetrahydrofuran / 1 h / 0 - 20 °C View Scheme
参考文献
Lambert, Joseph B.; So, Jeung-Ho
Journal of Organic Chemistry, 1991 , vol. 56, # 20 p. 5960 - 5962
反应条件
magnesium in tetrahydrofuran T=80°C; 0.333333 h; microwave irradiation;
参考文献
Zhao, Fei; Yu, Da-Gang; Zhu, Ru-Yi; Xi, Zhenfeng; Shi, Zhang-Jie
Chemistry Letters, 2011 , vol. 40, # 9 p. 1001 - 1003
反应条件
1: 1) Mg, ether / 2) THF, -45 grad C, 0.5 h 2: HCl / 1 h / 0 °C 3: 92 percent / sulphuryl chloride / CCl4 / 0.5 h / Ambient temperature View Scheme
参考文献
Freeman, Sally; Harger, Martin J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 1399 - 1406
反应条件
1: With ethyl orthosilicate; iodine; magnesium in tetrahydrofuran Heating; 2: With lithium aluminium tetrahydride in diethyl ether T=20°C;
参考文献
Minge, Oliver; Nogai, Stefan; Schmidbaur, Hubert
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2004 , vol. 59, # 2 p. 153 - 160
反应条件
1: sodium; benzene
2: diluted nitric acid / 115 - 130 °C / im geschlossenen Rohr
View Scheme
参考文献
Jannasch; Weiler
Chemische Berichte, 1894 , vol. 27, p. 3444
Chemische Berichte, 1895 , vol. 28, p. 531
