2,2-二甲基苯乙酸甲酯合成路线 （共 49 条）
反应条件
potassium carbonate T=220°C; 8 h;
参考文献
Selva, Maurizio; Marques, Carlos Alberto; Tundo, Pietro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 10 p. 1323 - 1328
反应条件
methanol in hexane; benzene T=20°C; 0.166667 h;
参考文献
Synthesis, , # 23 art. no. F16908SS, p. 3835 - 3845
反应条件
1: SOCl2 / 1 h 2: 1 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 108, # 14 p. 4119 - 4125
反应条件
RhH2(O2COH)(P(i-Pr)3)2 in tetrahydrofuran T=120°C; 20 h; Yield given. Further byproducts given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 23, # 47 p. 4967 - 4968
反应条件
sodium hydride in ethylene glycol dimethyl ether T=20 - 50°C;
参考文献
Merrell Pharmaceuticals Inc.
Patent: US6340761 B1, 2002 ;
Location in patent: Page column 47-48 ;
反应条件
1: 1.) NaH / 1.) 1,2-dimethoxyethane, reflux, 5 h, 2.) 1,2-dimethoxyethane, reflux, 15 h 2: tributyltin hydride, AIBN / benzene / 4 h / Heating View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 55, # 12 p. 3939 - 3940
反应条件
zinc dibromide T=115°C; 4 h;
参考文献
Synthesis, , # 4 p. 436 - 437
反应条件
1: 68 percent / benzene / Heating 2: 68 percent / H2SO4 / methanol / 9 h / Heating View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 28, # 7 p. 1229 - 1230
Zhurnal Organicheskoi Khimii, , vol. 28, # 7 p. 1546 - 1548
反应条件
1 h; Heating; Yield given;
参考文献
Journal of the American Chemical Society, , vol. 108, # 14 p. 4119 - 4125
参考文献
Bulletin de la Societe Chimique de France, , p. 787 - 790
