1,4-二甲基-5-硝基-咪唑合成路线 （共 13 条）
参考文献
Journal of the Chemical Society, , vol. 121, p. 2624
反应条件
1: 76 percent / dimethylsulfoxide / 67 h / 125 °C 2: 45 percent / di-n-butyltin oxide / 5.5 h / 150 °C View Scheme
参考文献
Walsh; Wang; Bagan; Wislocki; Miwa
Journal of Medicinal Chemistry, 1987 , vol. 30, # 1 p. 150 - 156
反应条件
in dimethyl sulfoxide T=125°C; 67 h;
参考文献
Walsh; Wang; Bagan; Wislocki; Miwa
Journal of Medicinal Chemistry, 1987 , vol. 30, # 1 p. 150 - 156
反应条件
hydrogenchloride; tin(ll) chloride DL-alanine;
参考文献
Pyman
Journal of the Chemical Society, 1922 , vol. 121, p. 2624
参考文献
Pyman
Journal of the Chemical Society, 1922 , vol. 121, p. 2624
反应条件
hydrogenchloride; tin(ll) chloride T=10°C;
参考文献
Pyman
Journal of the Chemical Society, 1922 , vol. 121, p. 2624
反应条件
formic acid; dimethyl sulfate in water
参考文献
BASF Aktiengesellschaft
Patent: US4021442 A1, 1977 ;
反应条件
trifluoroacetic acid in acetonitrile
5 h; Heating;
参考文献
Hosmane, Ramachandra S.; Bhan, Anila; Rauser, Michael E.
Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5892 - 5895
反应条件
in 1,4-dioxane
2 h; Heating;
参考文献
Chauviere, Gerard; Bouteille, Bernard; Enanga, Bertin; De Albuquerque, Cristina; Croft, Simon L.; Dumas, Michel; Perie, Jacques
Journal of Medicinal Chemistry, 2003 , vol. 46, # 3 p. 427 - 440
反应条件
potassium carbonate in N,N-dimethyl-formamide
24 h;
参考文献
Hosmane, Ramachandra S.; Bhan, Anila; Rauser, Michael E.
Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5892 - 5895
