6,7,8,9-四氢-5H-咪唑[1,2-a]氮杂卓合成路线 （共 9 条）
反应条件
tin(IV) chloride in dichloromethane; 1,3,5-trimethyl-benzene 45 h; Heating;
参考文献
Hua, Duy H.; Zhang, Fengqi; Chen, Jinshan; Robinson, Paul D.
Journal of Organic Chemistry, 1994 , vol. 59, # 17 p. 5084 - 5087
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in toluene 5 h; Heating;
参考文献
Aldabbagh, Fawaz; Bowman, W. Russell
Tetrahedron, 1999 , vol. 55, # 13 p. 4109 - 4122
反应条件
1: 1.) sodium borohydride / 1) ethanol, 0 deg C, 30 min; 2) ethanol, rt, 16 h 2: 64 percent / sodium iodide / acetone / 18 h / Heating 3: 1.) NaH / 1) acetonitrile, reflux, 1 h; 2) acetonitrile, reflux, 2 h 4: 63 percent / Bu3SnH, AIBN / toluene / 10 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 55, # 13 p. 4109 - 4122
反应条件
1: 1.) NaH / 1) acetonitrile, reflux, 1 h; 2) acetonitrile, reflux, 2 h 2: 63 percent / Bu3SnH, AIBN / toluene / 10 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 55, # 13 p. 4109 - 4122
反应条件
1: 64 percent / sodium iodide / acetone / 18 h / Heating 2: 1.) NaH / 1) acetonitrile, reflux, 1 h; 2) acetonitrile, reflux, 2 h 3: 63 percent / Bu3SnH, AIBN / toluene / 10 h / Heating View Scheme
参考文献
Tetrahedron, , vol. 55, # 13 p. 4109 - 4122
参考文献
Yoshitomi Pharmaceutical Industries, Ltd.
Patent: US6187774 B1, 2001 ;
参考文献
Yoshitomi Pharmaceutical Industries, Ltd.
Patent: US6187774 B1, 2001 ;
参考文献
Yoshitomi Pharmaceutical Industries, Ltd.
Patent: US6187774 B1, 2001 ;
反应条件
N-bromosuccinmide in tetrachloromethane 1 h;
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP1564213 A1, 2005 ;
Location in patent: Page/Page column 66-67 ;
