N-[1-[3-[2-(4-氟苯基)-1,3-二氧戊环-2-基]丙基]哌啶-4-基]苯-1,4-二胺合成路线 (共 7 条)
反应条件
carbon disulfide; potassium hydroxide in ethanol 3 h; Heating; Yield given;
参考文献
Sato; Arimoto
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 2 p. 719 - 722
反应条件
potassium iodide; sodium carbonate in ethanol; chloroform; benzene
参考文献
Daiichi Seiyaku Co., Ltd.
Patent: US3963727 A1, 1976 ;
反应条件
1: 77.4 percent / xylene / 13 h / Heating
2: NaBH4 / 2.5 h
View Scheme
参考文献
Sato; Arimoto
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 2 p. 719 - 722
反应条件
2: 77.4 percent / xylene / 13 h / Heating
3: NaBH4 / 2.5 h
View Scheme
参考文献
Sato; Arimoto
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 2 p. 719 - 722
反应条件
2: 77.4 percent / xylene / 13 h / Heating
3: NaBH4 / 2.5 h
View Scheme
参考文献
Sato; Arimoto
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 2 p. 719 - 722
反应条件
1: 77.4 percent / xylene / 13 h / Heating
2: NaBH4 / 2.5 h
View Scheme
参考文献
Sato; Arimoto
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 2 p. 719 - 722
反应条件
sodium tetrahydroborate
2.5 h;
参考文献
Sato; Arimoto
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 2 p. 719 - 722