2-氰基-1,1-联苯-2-羧酸合成路线 （共 16 条）
反应条件
potassium carbonate; 2-dicyclohexylphosphino-1,1'-biphenyl; palladium diacetate in acetonitrile
T=90°C; Suzuki coupling reaction; 20 h;
参考文献
Tao, Bin; Goel, Subhash C.; Singh, Jagvir; Boykin, David W.
Synthesis, 2002 , # 8 p. 1043 - 1046
反应条件
calcium hydroxide powder; N-benzyl-N,N,N-triethylammonium chloride; water; p-toluenesulfonyl chloride in toluene
2 h; Heating;
参考文献
Mysyk, D. D.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 8 p. 1568 - 1570
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 8 p. 1756 - 1758
反应条件
calcium hydroxide powder; N-benzyl-N,N,N-triethylammonium chloride; water; p-toluenesulfonyl chloride in toluene
2 h; Heating;
参考文献
Mysyk, D. D.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 8 p. 1568 - 1570
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 8 p. 1756 - 1758
反应条件
acetic anhydride; acetic acid
T=145°C;
参考文献
Underwood; Clough
Journal of the American Chemical Society, 1929 , vol. 51, p. 586
反应条件
1: 76 percent / aq. NaOH; KMnO4 / 3 h / 50 °C
2: 49 percent / aq. K2CO3; Cy2P(bi-Ph) / Pd(OAc)2 / acetonitrile / 20 h / 90 °C
View Scheme
参考文献
Tao, Bin; Goel, Subhash C.; Singh, Jagvir; Boykin, David W.
Synthesis, 2002 , # 8 p. 1043 - 1046
参考文献
Rapoport; Williams
Journal of the American Chemical Society, 1949 , vol. 71, p. 1774,1777
反应条件
1: NH3 / 0.17 h
2: CuCl, O2 / pyridine / 6 h
View Scheme
参考文献
Balogh-Hergovich, Eva; Speier, Gabor; Tyeklar, Zoltan
Synthesis, 1982 , # 9 p. 731 - 732
反应条件
oxygen; copper(l) chloride in pyridine
6 h; Yield given;
参考文献
Balogh-Hergovich, Eva; Speier, Gabor; Tyeklar, Zoltan
Synthesis, 1982 , # 9 p. 731 - 732
反应条件
1: benzene
2: Ac2O, HClO4
View Scheme
参考文献
Boyd,G.V.; Monteil,R.L.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1978 , p. 1338 - 1350
反应条件
thionyl chloride; sulfur dioxide
参考文献
Murakami; Tokura
Bulletin of the Chemical Society of Japan, 1958 , vol. 31, p. 1044,1047
