4-溴-1,3-二甲基-1H-吡唑-5-羧酸合成路线 （共 2 条）
反应条件
1: With sodium hydroxide in methanol T=20°C; 18 h; 2: With hydrogenchloride in methanol; water pH=5;
参考文献
WO2009/147188 A1, ;
Page/Page column 118-119 ;
WO 2009/147188 A1
反应条件
1.1: N-bromosuccinmide / chloroform / 12 h / 20 °C 2.1: potassium carbonate / acetone / 10 h / 50 °C 3.1: water; sodium hydroxide / methanol / 4 h / Reflux 3.2: pH 2 / Acidic conditions View Scheme
参考文献
Chinese Chemical Letters, , vol. 23, # 6 p. 669 - 672
