1: 4-pyridinecarbonitrile With sodium methylate in methanol T=20°C; 1 h; 2: Production of 2-cyanoisonicotinic acid hydrazide 1frac12; p-toluenesulfonic acid salt 24 h; reflux;

1: 4-pyridinecarbonitrile With sodium methylate T=20°C; 1 h; 2: 2-cyanoisonicotinic acid hydrazide 37 h; reflux;