3-(羟基甲基)-1-甲基-2-吡咯烷酮合成路线 （共 4 条）
反应条件
hydrogen; palladium 10 on activated carbon in methanol; water
T=20°C; 2 h;
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1479684 A1, 2004 ;
Location in patent: Page 20 ;
反应条件
sodium tetrahydroborate; calcium chloride in methanol
T=20°C; 14 h;
参考文献
Loreto, M. Antonietta; Migliorini, Antonella; Tardella, P. Antonio; Gambacorta, Augusto
European Journal of Organic Chemistry, 2007 , # 14 p. 2365 - 2371
反应条件
1: 45 percent / NaH / toluene / 8 h / Heating
2: 80 percent / NaBH4; CaCl2 / methanol / 14 h / 20 °C
View Scheme
参考文献
Loreto, M. Antonietta; Migliorini, Antonella; Tardella, P. Antonio; Gambacorta, Augusto
European Journal of Organic Chemistry, 2007 , # 14 p. 2365 - 2371
反应条件
copper(l) iodide; dicyclohexyl-carbodiimide in toluene
1.16667 h; Heating;
参考文献
Loreto, M. Antonietta; Migliorini, Antonella; Tardella, P. Antonio; Gambacorta, Augusto
European Journal of Organic Chemistry, 2007 , # 14 p. 2365 - 2371
