7-甲氧基他克林;9-氨基-7-甲氧基-1,2,3,4-四氢吖啶合成路线 （共 5 条）
反应条件
pyridine hydrochloride T=180°C; 4 h;
参考文献
Del Giudice; Borioni; Mustazza; Gatta; Meneguz; Volpe
Farmaco, 1996 , vol. 51, # 11 p. 693 - 698
反应条件
ammonia; phenol
T=180 - 190°C; 4 h;
参考文献
Del Giudice; Borioni; Mustazza; Gatta; Meneguz; Volpe
Farmaco, 1996 , vol. 51, # 11 p. 693 - 698
反应条件
sodium hydroxide; nickel monoaluminide in 1,4-dioxane
3 h; Irradiation;
参考文献
Kamata, Kichinosuke; Tominaga, Yoh-Ichi; Tori-I, Akiyoshi; Thiemann, Thies; Takahashi, Kazufumi; Mataka, Shuntaro
Heterocycles, 2002 , vol. 57, # 9 p. 1683 - 1688
反应条件
1: p-TsOH*H2O / toluene / 8 h / Heating
2: diphenyl ether / 0.5 h / Heating
3: 87 percent / POCl3 / 1 h / Heating
4: 70 percent / NH3, phenol / 4 h / 180 - 190 °C
View Scheme
参考文献
Del Giudice; Borioni; Mustazza; Gatta; Meneguz; Volpe
Farmaco, 1996 , vol. 51, # 11 p. 693 - 698
反应条件
1: p-TsOH*H2O / toluene / 8 h / Heating
2: diphenyl ether / 0.5 h / Heating
3: 87 percent / POCl3 / 1 h / Heating
4: 70 percent / NH3, phenol / 4 h / 180 - 190 °C
View Scheme
参考文献
Del Giudice; Borioni; Mustazza; Gatta; Meneguz; Volpe
Farmaco, 1996 , vol. 51, # 11 p. 693 - 698
