4-羟基-2-甲基苯甲酸合成路线 (共 37 条)
参考文献
Chemische Berichte, , vol. 11, p. 700,773
参考文献
Chemische Berichte, , vol. 14, p. 40
参考文献
Chemische Berichte, , vol. 17, p. 161
反应条件
caesium carbonate in N,N-dimethyl-formamide T=0 - 20°C;
参考文献
ARAGON PHARMACEUTICALS, INC.; KAHRAMAN, Mehmet; GOVEK, Steven, P.; NAGASAWA, Johnny, Y.; SMITH, Nicholas, D.
Patent: WO2011/156518 A2, 2011 ;
Location in patent: Page/Page column 115 ;
WO 2011/156518 A2
参考文献
Peltier
Bulletin de la Societe Scientifique de Bretagne, 1956 , vol. 31, p. Sonderheft S.9,41
反应条件
1,2-dichloro-ethane in hexane; ethyl acetate; N,N-dimethyl-formamide
参考文献
G.D. Searle and Co.
Patent: US6046190 A1, 2000 ;
US 6046190 A
参考文献
Jacobsen
Chemische Berichte, 1881 , vol. 14, p. 40
参考文献
Jacobsen
Chemische Berichte, 1881 , vol. 14, p. 40
反应条件
borane-THF in tetrahydrofuran
T=20 - 80°C; Inert atmosphere;
参考文献
Sebej, Peter; Lim, Bum Hee; Park, Bong Ser; Givens, Richard S.; Klan, Petr
Organic Letters, 2011 , vol. 13, # 4 p. 644 - 647
反应条件
1: hydrogen chloride
3: beim Erhitzen ueber den Schmelzpunkt
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参考文献
Gomberg; Johnson
Journal of the American Chemical Society, 1917 , vol. 39, p. 1680