6-甲氧基-2-苯基-1H-吲哚合成路线 （共 18 条）
反应条件
rhodium(II) heptafluorobutyrate in toluene
T=60°C; 16 h; Molecular sieve;
参考文献
Shen, Meihua; Leslie, Brooke E.; Driver, Tom G.
Angewandte Chemie - International Edition, 2008 , vol. 47, # 27 p. 5056 - 5059
反应条件
trifluoroacetic acid in dichloromethane
T=20°C;
参考文献
KISSEI PHARMACEUTICAL CO., LTD.
Patent: US2012/122931 A1, 2012 ;
Location in patent: Page/Page column 20 ;
反应条件
tetrabutylammomium bromide; oxygen; palladium diacetate in dimethyl sulfoxide
T=60°C; P=760.051 Torr; 24 h;
参考文献
Wei, Ye; Deb, Indubhusan; Yoshikai, Naohiko
Journal of the American Chemical Society, 2012 , vol. 134, # 22 p. 9098 - 9101
反应条件
zinc dibromide in toluene
24 h; Reflux;
参考文献
Okuma, Kentaro; Seto, Jun-ichi; Sakaguchi, Ken-ichi; Ozaki, Saori; Nagahora, Noriyoshi; Shioji, Kosei
Tetrahedron Letters, 2009 , vol. 50, # 24 p. 2943 - 2945
反应条件
triethylamine; palladium diacetate; tris-(o-tolyl)phosphine in acetonitrile
T=100°C; 20 h; sealed tube;
参考文献
Kasahara, Akira; Izumi, Taeko; Kikuchi, Tokio; Xiao-ping Lin
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1555 - 1556
反应条件
[Ru(CO)2(4,5-bis(diphenylphosphino)-9,9-dimethyl-9H-xanthene)]2; [Ru(CO)2(4,5-bis(diphenylphosphino)-9,9-dimethyl-9H-xanthene)]2; toluene-4-sulfonic acid in 1,1-dimethylpropan-1-ol
T=120°C; regioselective reaction;
参考文献
Zhang, Min; Xie, Feng; Wang, Xiaoting; Yan, Fengxia; Wang, Ting; Chen, Mengmeng; Ding, Yuqiang
RSC Advances, 2013 , vol. 3, # 17 p. 6022 - 6029
反应条件
copper diacetate; palladium diacetate in dimethyl sulfoxide
T=40°C; 12 h; Inert atmosphere;
参考文献
Wei, Ye; Deb, Indubhusan; Yoshikai, Naohiko
Journal of the American Chemical Society, 2012 , vol. 134, # 22 p. 9098 - 9101
反应条件
carbon monoxide; sulfur; triethylamine in N,N-dimethyl-formamide
T=150°C; P=22801.5 Torr; 24 h; Autoclave;
参考文献
Umeda, Rui; Nishimoto, Yuuta; Mashino, Tsukasa; Nishiyama, Yutaka
Heterocycles, 2013 , vol. 87, # 6 p. 1241 - 1247
反应条件
1: 83 percent / TEA / toluene / 3 h / Heating
2: 1.) n-BuLi, 2.) 2N aq. HCl / 1.) hexane, THF, RT, 20 h, 2.) hexane, THF, 0 deg C
View Scheme
参考文献
Tarzia, Giorgio; Diamantini, Giuseppe; Di Giacomo, Barbara; Spadoni, Gilberto; Esposti, Daniele; Nonno, Romolo; Lucini, Valeria; Pannacci, Marilou; Fraschini, Franco; Stankov, Bojidar Michaylov
Journal of Medicinal Chemistry, 1997 , vol. 40, # 13 p. 2003 - 2010
反应条件
1: 66 percent / Et3N / PdCl2(PPh3)2, CuI / 3 h / Heating
2: 88 percent / TBAF / tetrahydrofuran / 24 h / Heating
View Scheme
参考文献
Yasuhara, Akito; Kanamori, Yuichi; Kaneko, Masashi; Numata, Atsushi; Kondo, Yoshinori; Sakamoto, Takao
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 4 p. 529 - 534
