2-(4-甲氧基苯基)-1H-吲哚合成路线 （共 67 条）
反应条件
carbon monoxide; triethylamine; selenium in N,N-dimethyl-formamide
T=100°C; Cyclization; reduction; P=3800 Torr; 5 h;
参考文献
Nishiyama, Yutaka; Maema, Ryo; Ohno, Kengou; Hirose, Masaharu; Sonoda, Noboru
Tetrahedron Letters, 1999 , vol. 40, # 31 p. 5717 - 5720
反应条件
sodium hydroxide in ethanol; water
T=70°C; 0.166667 h;
参考文献
Thielges, Sabine; Meddah, Emilie; Bisseret, Philippe; Eustache, Jacques
Tetrahedron Letters, 2004 , vol. 45, # 5 p. 907 - 910
反应条件
1,1'-bis-(diphenylphosphino)ferrocene; potassium carbonate; palladium diacetate in toluene
T=110°C; 48 h;
参考文献
Bellina, Fabio; Benelli, Francesca; Rossi, Renzo
Journal of Organic Chemistry, 2008 , vol. 73, # 14 p. 5529 - 5535
反应条件
1: With copper(l) iodide; potassium carbonate; N-methyl-2-(methylamino)ethylamine in toluene
T=105°C; 24 h; Inert atmosphere;
2: With trifluoroacetic acid in dichloromethane
T=23°C; 2 h; Inert atmosphere;
参考文献
Ackermann, Lutz; Barfuesser, Sebastian; Potukuchi, Harish K.
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 7-8 p. 1064 - 1072
反应条件
potassium tert-butylate; palladium diacetate; triphenylphosphine in dimethyl sulfoxide
T=20 - 120°C; intramolecular Heck reaction; Inert atmosphere;
参考文献
Mao, Hui; Wan, Jie-Ping; Pan, Yuanjiang; Sun, Cuirong
Tetrahedron Letters, 2010 , vol. 51, # 14 p. 1844 - 1846
反应条件
sulfuric acid; silver(I) acetate; palladium dichloride in N,N-dimethyl-formamide; acetonitrile
T=100°C; 0.666667 h; Sealed tubeMicrowave irradiation; regioselective reaction;
参考文献
Miao, Tao; Li, Pinhua; Wang, Guan-Wu; Wang, Lei
Chemistry - An Asian Journal, 2013 , vol. 8, # 12 p. 3185 - 3190
反应条件
1: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine in N,N-dimethyl acetamide
T=20°C; Sonogashira Cross-Coupling; 1 h;
2: With sodium hydroxide in N,N-dimethyl acetamide
T=140°C;
参考文献
Yu, Xufen; Park, Eun-Jung; Kondratyuk, Tamara P.; Pezzuto, John M.; Sun, Dianqing
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 44 p. 8835 - 8847
反应条件
GIPKh-115 in benzene
(g) phase;
参考文献
Suvorov, N. N.; Shkil'kova, V. N.; Podkhalyuzina, N. Ya.
Journal of Organic Chemistry USSR (English Translation), 1983 , p. 2117 - 2120
Zhurnal Organicheskoi Khimii, 1983 , vol. 19, # 11 p. 2420 - 2423
反应条件
Au/Carbon G-60 catalyst in toluene
T=70°C; 96 h; Schlenk technique;
参考文献
Perea-Buceta, Jesus E.; Wirtanen, Tom; Laukkanen, Otto-Ville; Maekelae, Mikko K.; Nieger, Martin; Melchionna, Michele; Huittinen, Nina; Lopez-Sanchez, Jose A.; Helaja, Juho
Angewandte Chemie - International Edition, 2013 , vol. 52, # 45 p. 11835 - 11839
Angew. Chem., 2013 , vol. 125, # 45 p. 12051 - 12055,5
反应条件
Au/Carbon G-60 catalyst in toluene
T=90°C; 48 h; Inert atmosphereSchlenk technique;
参考文献
Perea-Buceta, Jesus E.; Wirtanen, Tom; Laukkanen, Otto-Ville; Maekelae, Mikko K.; Nieger, Martin; Melchionna, Michele; Huittinen, Nina; Lopez-Sanchez, Jose A.; Helaja, Juho
Angewandte Chemie - International Edition, 2013 , vol. 52, # 45 p. 11835 - 11839
Angew. Chem., 2013 , vol. 125, # 45 p. 12051 - 12055,5
