2-(4-甲氧基苯基)-1H-吲哚合成路线 （共 67 条）
反应条件
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / 10 h / 20 - 40 °C / |Inert atmosphere; |Schlenk technique
2: Au/Carbon G-60 catalyst / toluene / 48 h / 90 °C / |Inert atmosphere; |Schlenk technique
View Scheme
参考文献
Perea-Buceta, Jesus E.; Wirtanen, Tom; Laukkanen, Otto-Ville; Maekelae, Mikko K.; Nieger, Martin; Melchionna, Michele; Huittinen, Nina; Lopez-Sanchez, Jose A.; Helaja, Juho
Angewandte Chemie - International Edition, 2013 , vol. 52, # 45 p. 11835 - 11839
Angew. Chem., 2013 , vol. 125, # 45 p. 12051 - 12055,5
反应条件
1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine / 6 h / 20 - 40 °C / |Inert atmosphere; |Schlenk technique
2: Au/Carbon G-60 catalyst / toluene / 96 h / 70 °C / |Schlenk technique
View Scheme
参考文献
Perea-Buceta, Jesus E.; Wirtanen, Tom; Laukkanen, Otto-Ville; Maekelae, Mikko K.; Nieger, Martin; Melchionna, Michele; Huittinen, Nina; Lopez-Sanchez, Jose A.; Helaja, Juho
Angewandte Chemie - International Edition, 2013 , vol. 52, # 45 p. 11835 - 11839
Angew. Chem., 2013 , vol. 125, # 45 p. 12051 - 12055,5
反应条件
ethanol; sodium ethanolate
und anschliessenden Erwaermen mit Methyljodid;
参考文献
Ames et al.
Journal of the Chemical Society, 1959 , p. 3388,3396
反应条件
1: zinc chloride
2: ethanol; sodium ethylate / und anschliessenden Erwaermen mit Methyljodid
View Scheme
参考文献
Ames et al.
Journal of the Chemical Society, 1959 , p. 3388,3396
反应条件
trichlorophosphate
1.) RT, 1 h, 2.) 30-35 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Nyerges, Miklos; Pinter, Aron; Viranyi, Andrea; Bitter, Istvan; Toke, Laszlo
Tetrahedron Letters, 2005 , vol. 46, # 3 p. 377 - 380
反应条件
1) C2H5OH, heating; 2) 1 min, heating; Yield given. Multistep reaction;
参考文献
Tiwari; Satsangi
Pharmazie, 1980 , vol. 35, # 12 p. 742 - 743
反应条件
1) C2H5OH, heating; 2) 1 min, heating; Yield given. Multistep reaction;
参考文献
Tiwari; Satsangi
Pharmazie, 1980 , vol. 35, # 12 p. 742 - 743
