3-碘-N-苯基-2-吡啶羧酰胺合成路线 （共 4 条）
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 2.33333 h; 2: With iodine in tetrahydrofuran; hexane T=-78 - 20°C; 3.16667 h; Further stages.;
参考文献
Markey, Michael D.; Ying, Fu; Kelly, T. Ross
Organic Letters, 2007 , vol. 9, # 17 p. 3255 - 3257
反应条件
1.1: oxalyl chloride; DMF / CH2Cl2 / 9 h / 0 - 20 °C 1.2: 74 percent / triethylamine / CH2Cl2 / 3 h / 0 - 20 °C 2.1: n-BuLi / tetrahydrofuran; hexane / 2.33 h / -78 °C 2.2: 63 percent / iodine / tetrahydrofuran; hexane / 3.17 h / -78 - 20 °C View Scheme
参考文献
Organic Letters, , vol. 9, # 17 p. 3255 - 3257
反应条件
1.1: oxalyl chloride; DMF / CH2Cl2 / 9 h / 0 - 20 °C 1.2: 74 percent / triethylamine / CH2Cl2 / 3 h / 0 - 20 °C 2.1: n-BuLi / tetrahydrofuran; hexane / 2.33 h / -78 °C 2.2: 63 percent / iodine / tetrahydrofuran; hexane / 3.17 h / -78 - 20 °C View Scheme
参考文献
Organic Letters, , vol. 9, # 17 p. 3255 - 3257
反应条件
hydrogenchloride 15 h; Heating;
参考文献
Epsztajn; Plotka; Grabowska
Synthetic Communications, 1997 , vol. 27, # 6 p. 1075 - 1086
