反-3-甲氧基丙烯酸甲酯合成路线 （共 30 条）
反应条件
potassium tert-butylate
参考文献
Journal of Organic Chemistry, , vol. 31, p. 646 - 655
反应条件
iodine in cyclohexane T=100°C; Equilibrium constantThermodynamic data;
参考文献
Journal of Organic Chemistry, , vol. 35, # 10 p. 3352 - 3358
参考文献
Canadian Journal of Chemistry, , vol. 52, p. 3569 - 3576
反应条件
(i), (ii) TsOH; Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 35, # 10 p. 3352 - 3358
参考文献
Tetrahedron Letters, , vol. 29, # 46 p. 5919 - 5922
反应条件
40 h; Heating; Further byproducts given;
参考文献
Phosphorus and Sulfur and the Related Elements, , vol. 22, p. 225 - 230
反应条件
40 h; Heating; Further byproducts given;
参考文献
Phosphorus and Sulfur and the Related Elements, , vol. 22, p. 225 - 230
反应条件
1: With sodium hydroxide; water T=40°C; pH=9.0 - 9.5; 4 h; 2: With hydrogenchloride in water T=5°C; pH=3 - 4;
参考文献
ARRAY BIOPHARMA INC.
Patent: WO2009/42435 A1, 2009 ;
Location in patent: Page/Page column 90-91; 94 ;
WO 2009/042435 A1
反应条件
in methanol T=90°C; 12 - 18 h;
参考文献
PFIZER INC.
Patent: WO2009/69044 A1, 2009 ;
Location in patent: Page/Page column 130; 141 ;
WO 2009/069044 A1
反应条件
1: With Tedicyp; sodium hydrogencarbonate; bis(η3-allyl-μ-chloropalladium(II)) in N,N-dimethyl-formamide T=150°C; Heck reaction; 20 h; 2: With hydrogenchloride in dichloromethane; water T=25°C;
参考文献
Battace, Ahmed; Feuerstein, Marie; Lemhadri, Mhamed; Zair, Touriya; Doucet, Henri; Santelli, Maurice
European Journal of Organic Chemistry, 2007 , # 19 p. 3122 - 3132
