3-乙酰氧基-2-环己烯-1-酮合成路线 （共 18 条）
反应条件
1: (photolysis) 2: KOtBu / 2-methyl-propan-2-ol 3: (photolysis) 4: (reduction) View Scheme
参考文献
Eaton,P.E.; Nyi,K.
Journal of the American Chemical Society, 1971 , vol. 93, p. 2786 - 2788
反应条件
1: (photolysis) 2: KOtBu / 2-methyl-propan-2-ol 3: (photolysis) View Scheme
参考文献
Eaton,P.E.; Nyi,K.
Journal of the American Chemical Society, 1971 , vol. 93, p. 2786 - 2788
反应条件
potassium cyanide; triethylamine in acetonitrile
T=20°C; 72 h;
参考文献
ECOBIOTICS LIMITED
Patent: WO2007/70986 A1, 2007 ;
Location in patent: Page/Page column 17; 44-46 ;
反应条件
potassium cyanide; triethylamine in acetonitrile
参考文献
Montes, Imber Flores; Burger, Ulrich
Tetrahedron Letters, 1996 , vol. 37, # 7 p. 1007 - 1010
反应条件
zinc(II) iodide in benzene
2.5 h; Ambient temperature;
参考文献
Shimizu, Makoto; Ando, Ryoichi; Kuwajima, Isao
Journal of Organic Chemistry, 1984 , vol. 49, # 7 p. 1230 - 1238
反应条件
1: 89 percent / zinc iodide / benzene / 2.5 h / Ambient temperature
2: diethyl ether / 0.67 h / -78 °C
3: m-CPBA, K2HPO4 / methanol / Ambient temperature
View Scheme
参考文献
Shimizu, Makoto; Ando, Ryoichi; Kuwajima, Isao
Journal of Organic Chemistry, 1984 , vol. 49, # 7 p. 1230 - 1238
反应条件
1: 89 percent / zinc iodide / benzene / 2.5 h / Ambient temperature
2: diethyl ether / 1) -78 deg C, 20 min, 2) 0 deg C, 10 min
3: m-CPBA, K2HPO4 / methanol / 2 h / Ambient temperature
View Scheme
参考文献
Shimizu, Makoto; Ando, Ryoichi; Kuwajima, Isao
Journal of Organic Chemistry, 1984 , vol. 49, # 7 p. 1230 - 1238
反应条件
1: With AlCl3, aluminium chloride in anhydrous dichloroethane
T=20°C; 2 h; Inert atmosphere;
2: With sulfuric acid in anhydrous dichloroethane; water
Inert atmosphereCooling with ice;
参考文献
ADDEX PHARMA S.A.; BOLEA, Christelle; SYLVAIN, Celanire
Patent: WO2010/79238 A1, 2010 ;
Location in patent: Page/Page column 31 ;
WO 2010/079238 A1
