3-(2-羟基乙氧基)苯甲腈合成路线 （共 4 条）
反应条件
1: With sodium tetrahydroborate in ethanol
T=50°C; 15 h;
2: With water in ethyl acetate
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP1953148 A1, 2008 ;
Location in patent: Page/Page column 118 ;
EP 1953148 A1
反应条件
1: With lithium hydroxide; water in tetrahydrofuran; methanol
T=0 - 20°C; 0.75 h;
2: With hydrogenchloride in tetrahydrofuran; methanol; water
T=0°C;
参考文献
AJINOMOTO CO., INC.
Patent: WO2006/83003 A1, 2006 ;
Location in patent: Page/Page column 31 ;
参考文献
Boyd; Marle
Journal of the Chemical Society, 1914 , vol. 105, p. 2123
参考文献
Boyd; Marle
Journal of the Chemical Society, 1914 , vol. 105, p. 2123
