4-(3-羟苯基)苯甲酸甲酯合成路线 （共 5 条）
反应条件
2-(N,N-dimethylamino)-pyridine; palladium (II) trifluoroacetate; oxygen; toluene-4-sulfonic acid in dimethyl sulfoxide T=80°C; P=760.051 Torr; 24 h;
参考文献
Izawa, Yusuke; Pun, Doris; Stahl, Shannon S.
Science, 2011 , vol. 333, # 6039 p. 209 - 213
反应条件
1: 4-Bromo-benzoic acid methyl ester With methanol; tetrahydroxydiboron; XPhos-Pd-G2; potassium acetate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl T=80°C; Suzuki-Miyaura Coupling; 2 h; Inert atmosphere; 2: m-monochlorophenol With potassium carbonate in water T=80°C; Suzuki Coupling; 15 h; Inert atmosphere;
参考文献
Molander, Gary A.; Trice, Sarah L. J.; Kennedy, Steven M.
Journal of Organic Chemistry, 2012 , vol. 77, # 19 p. 8678 - 8688
参考文献
US2004/6071 A1, ;
Page/Page column 18-19 ;
反应条件
in 1-methyl-pyrrolidin-2-one; dimethyl sulfoxide T=80°C; 32 h;
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 13 p. 3672 - 3675
Angew. Chem., , vol. 125, # 13 p. 3760 - 3763,4
反应条件
1: [Pd(CH3CN)4](BF4)2; 6,6'-dimethyl-2,2'-bipyridine; anthraquinone-2-sulfonic acid sodium salt; oxygen / 1-methyl-pyrrolidin-2-one / 4 h / 50 °C / 760.05 Torr 2: dimethyl sulfoxide; 1-methyl-pyrrolidin-2-one / 32 h / 80 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 52, # 13 p. 3672 - 3675
Angew. Chem., , vol. 125, # 13 p. 3760 - 3763,4
