1-(乙酰氨基)-1-苯乙烯合成路线 （共 32 条）
反应条件
1: methyl-magnesium iodide; benzonitrile in diethyl ether
2: acetic anhydride 1 h; Cooling with isopropanol-dry ice;
参考文献
Crosman, Adrian; Hoelderich, Wolfgang F.
Journal of Catalysis, 2009 , vol. 265, # 2 p. 229 - 237
反应条件
(S)-diBr-SIPHOS; hydrogen; rhodium(I)-bis(1,5-cyclooctadiene) tetrafluoroborate in toluene
T=0°C; P=38000 Torr; 30 h;
参考文献
Chen, Weiping; Roberts, Stanley M.; Whittall, John
Tetrahedron Letters, 2006 , vol. 47, # 25 p. 4263 - 4266
反应条件
lt;lt;(R,R)-1,2-bis(trans-2,5-dimethylphospholano)ethanegt;Rh(COD)gt;OTf; hydrogen in methanol
T=22°C; P=3102.9 Torr; 15 h; var. rhodium chiral complexes and solvents; other aryl enamides; Product distribution;
参考文献
Hayashi, Minoru; Hashimoto, Yukihiko; Takezaki, Hiroshi; Watanabe, Yuichiro; Saigo, Kazuhiko
Tetrahedron Asymmetry, 1998 , vol. 9, # 11 p. 1863 - 1866
反应条件
[bis(acetoxy)iodo]benzene; boron trifluoride diethyl etherate in 1,2-dichloro-ethane
0.5 h; Reflux;
参考文献
Zheng, Yunhui; Li, Xuming; Ren, Chengfeng; Zhang-Negrerie, Daisy; Du, Yunfei; Zhao, Kang
Journal of Organic Chemistry, 2012 , vol. 77, # 22 p. 10353 - 10361
反应条件
18-crown-6 ether; cesium fluoride in tetrahydrofuran
T=80°C; 24 h; Inert atmosphere; chemoselective reaction;
参考文献
Zhao, Mi-Na; Ren, Zhi-Hui; Wang, Yao-Yu; Guan, Zheng-Hui
Chemical Communications, 2012 , vol. 48, # 65 p. 8105 - 8107
反应条件
18-crown-6 ether; cesium fluoride in tetrahydrofuran
T=80°C; chemoselective reaction;
参考文献
Zhao, Mi-Na; Ren, Zhi-Hui; Wang, Yao-Yu; Guan, Zheng-Hui
Chemical Communications, 2012 , vol. 48, # 65 p. 8105 - 8107
反应条件
oxygen; potassium acetate; palladium diacetate in dimethyl sulfoxide
T=80°C; P=760.051 Torr; 24 h; Overall yield = 60 percent;
参考文献
Xu, Yun-He; He, Tao; Zhang, Qiu-Chi; Loh, Teck-Peng
Chemical Communications, 2014 , vol. 50, # 21 p. 2784 - 2786
反应条件
1,4-diaza-bicyclo[2.2.2]octane; carbon monoxide; copper diacetate; palladium diacetate; acetic anhydride; potassium iodide in N,N-dimethyl-formamide
T=80°C; Reagent/catalystSolvent;
参考文献
Chen, Ming; Ren, Zhi-Hui; Wang, Yao-Yu; Guan, Zheng-Hui
Angewandte Chemie - International Edition, 2013 , vol. 52, # 52 p. 14196 - 14199
Angew. Chem., 2013 , vol. 125, # 52 p. 14446 - 14449,4
反应条件
oxygen; potassium acetate; palladium diacetate in dimethyl sulfoxide
T=80°C; P=760.051 Torr; 24 h;
参考文献
Xu, Yun-He; He, Tao; Zhang, Qiu-Chi; Loh, Teck-Peng
Chemical Communications, 2014 , vol. 50, # 21 p. 2784 - 2786
反应条件
copper(l) iodide; glycine in 1,4-dioxane
T=140°C; 30 h; chemoselective reaction;
参考文献
Zhao, Mi-Na; Ren, Zhi-Hui; Wang, Yao-Yu; Guan, Zheng-Hui
Chemical Communications, 2012 , vol. 48, # 65 p. 8105 - 8107
