5,5-二甲基-4-氧代己酸合成路线 （共 8 条）
反应条件
1: With potassium hydroxide in methanol; water 2 h; Reflux; 2: With hydrogenchloride in methanol; water
参考文献
Sedlacek, Ondrej; Hruby, Martin; Studenovsky, Martin; Vetvicka, David; Svoboda, Jan; Kankova, Dana; Kovar, Jan; Ulbrich, Karel
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 13 p. 4056 - 4063
反应条件
potassium hydroxide in ethanol 2 h; Heating;
参考文献
Kunkel, Elisabeth; Reichelt, Ingrid; Reissig, Hans-Ulrich
Liebigs Annalen der Chemie, 1984 , # 4 p. 802 - 819
反应条件
1: aq. KOH / ethanol / 2 h / Heating 2: methanol; H2O / 0.5 h / Heating View Scheme
参考文献
Chemische Berichte, , vol. 116, # 1 p. 220 - 229
反应条件
1.1: sodium methylate / methanol / 0.5 h 1.2: 2 h / Reflux 2.1: potassium hydroxide / methanol; water / 2 h / Reflux View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 20, # 13 p. 4056 - 4063
反应条件
lithium amide; ammonia anschliessend mit Bromessigsaeure und Aether;
参考文献
Lantbruks Hoegskol Ann., , vol. 25, p. 363,371
参考文献
Journal of the American Chemical Society, , vol. 59, p. 2385
反应条件
in methanol; water 0.5 h; Heating; Yield given;
参考文献
Chemische Berichte, , vol. 116, # 1 p. 220 - 229
反应条件
1: 5 percent KOH 2: 108 °C / Schmelzen View Scheme
参考文献
Chemische Berichte, , vol. 65, p. 1857,1862
