5-溴-N,2-二羟基苯甲酰胺合成路线 （共 3 条）
参考文献
Buu-Hoi et al.
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1953 , vol. 236, p. 635
反应条件
1: With thionyl chloride in tetrahydrofuran
T=10 - 20°C; 2 h;
2: With triethylamine in 1,4-dioxane
T=0 - 20°C;
参考文献
PHENEX PHARMACEUTICALS AG; KREMOSER, Claus; ABEL, Ulrich; STEENECK, Christoph; KINZEL, Olaf
Patent: WO2011/20615 A1, 2011 ;
Location in patent: Page/Page column 75; 76 ;
反应条件
1: HCl / acetic acid
2: aq. NH3
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参考文献
Reisner; Ludwig; Stiefel; Gister; Meyer; Powell; Sofia
Arzneimittel-Forschung/Drug Research, 1977 , vol. 27, # 4 p. 760 - 766
